Standardize tumor classification and variant annotation for reproducible cohort building with COSMIC

Accurate interpretation of cancer genomics depends on standardized disease classification, tumor characterization and variant annotation. In this joint COSMIC and QIAGEN webinar, we show how these robust frameworks enable reliable cohort building and reproducible research.
 
The webinar covers three themes: 

• Disease classification: COSMIC’s tumor classification and mapping to NCI Thesaurus and EFO. 
• Tumor site and histology subtyping: COSMIC’s highly detailed classification system, conversion of histologies into controlled terms, and how these support construction of focused cohorts and studying rare cancer types.
• Variant annotation: COSMIC gene identifiers, cross-mapping strategies and annotation conversion. 

The session explains COSMIC’s approach, its benefits, common challenges, and practical use cases, combining high-level overviews with technical detail and reproducible demonstrations.
 
By attending this webinar, you will gain:

• A clear understanding of COSMIC disease classification
• Guidance on mapping to external ontologies (e.g. NCI Thesaurus)
• Insight into how detailed tumor subtyping supports precise cohort building
• An understanding of variant cross-mapping
• Practical strategies for converting COSMIC annotations for downstream analysis
• Demonstrations of reproducible analyses and COSMIC data integration