From RNA to Rapid Decisions: Using Immune Signals to Improve ED Patient Disposition

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Sepsis and acute infection remain among the most challenging conditions in emergency and critical care, where high-stakes decisions must be made early with incomplete information. Delays and diagnostic uncertainty contribute to prolonged emergency department (ED) wait times, increased length of stay, and downstream throughput constraints. This webinar explores how immune-response diagnostics, enabled by high-quality RNA preanalytics, are emerging as a new standard to improve early risk stratification, patient disposition and resource utilization at the front end of care.

This session is designed for laboratory leaders, clinicians, and hospital administrators seeking practical, evidence-based guidance on implementing immune-response testing and the pre-analytical workflows that enable it..

Learning Objectives: 

1. Understand why early sepsis and acute infection decision-making remains challenging and how risk stratification based on a patient’s acute immune response adds clinical and operational value beyond traditional pathogen-based approaches.
2. Describe how immune-based decision support can result in earlier recognition of high-risk patients, better ED disposition decisions based on risk stratification, reductions in avoidable admissions and transfers, and greater support for sepsis workflows.
3. Recognize the critical role of sampling and preanalytical variables in host immune-response IVD assay development and clinical implementation, particularly for blood RNA–based assays.
4. Apply standardized PAXgene Blood RNA workflows to minimize preanalytical variability, preserve RNA integrity, and improve test repeatability, reliability, and clinical confidence.